Pre-PLOS "common wisdom": only way to make journals work is by paid subscriptions and closed access articles. Present "common wisdom": PLOS proved you can run

Pre-PLOS "common wisdom": only way to make journals work is by paid subscriptions and closed access articles. Present "common wisdom": PLOS proved you can run a high-profile, open access journal and be a real business. Future (who wants to take on this challenge?): Run an open access, high profile journal that charges less than $100/ article to publish. .... Current price for each published article in PLOS: PLOS Biology $2,900 USD PLOS Medicine $2,900 USD PLOS Computational Biology $2,250 USD PLOS Genetics $2,250 USD PLOS Pathogens $2,250 USD PLOS Neglected Tropical Diseases $2,250 USD PLOS ONE $1,495 USD PLOS Genetics has something like 720 articles published per year so you can do the math on what they make from those fees.