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I attended a really good guest lecture by Dr.David Reich (with additional work also by Dr.Nick Patterson) on analyzing ancient DNA. "Massive migration from the
by noname123 11y ago
I attended a really good guest lecture by Dr.David Reich (with additional work also by Dr.Nick Patterson) on analyzing ancient DNA.
"Massive migration from the [Anatolian] steppe is a source for Indo-European languages in Europe"
I can't find the slides/video recording anywhere (it's a shame because it was the most accessible presentation on genetics I found to everyone).
Dr.Reich didn't go into too much technical details during the lecture; the audience was to a bunch of undergrad and first year grad students interested in computational biology; and guest lecturers are PIs around the Boston area who are trying to recruit for students into their labs.
However, he did hint some of analysis they did to construct the migration path came from the distribution of particular classes of metabolic genes for different diets; meaning, early human beings can be classified as farmers (grain-based diet), hunter-gatherers (raw meat) and nomadic people (consume more animal products, lactose); by collecting samples collected in Europe, carbon-dating them and constructing phylogeny tree (most percentage of shared single nucleotide polymorphism are classified as siblings, least likely amount of base mutations to the target offsprings are labeled as parents) amongst the samples and classifying them amongst these three diet-based cohorts and sample-collection sites, you can begin to construct a likely migratory path.
Also Dr.Riech also made an interesting point that the reason why most ancient DNA research is done in Europe and not really in Africa which would seem more logical is because: most grants to do the work come from European scientific agencies who have mandates to fund their own anthropology and culture studies (an unintended "Eurocentric" side-affect of research grants).
Here is the Nature article instead:
http://www.nature.com/nature/journal/v522/n7555/abs/nature14317.html http://www.nature.com/nature/journal/v522/n7555/abs/nature14...
Non-paywall version: http://arxiv.org/pdf/1502.02783.pdf http://arxiv.org/pdf/1502.02783.pdf
- danieltillett 11y agoOne of the other reasons is DNA survives best at low temperature. Unfortunately there are not many places in Africa where the temperature is low enough to have DNA survive 10,000s of years.