Do you think Study 329 was productive research? (Productive for patients, that is, as was productive for GSK's income.) If a study is always adjusted then how

Do you think Study 329 was productive research? (Productive for patients, that is, as was productive for GSK's income.) If a study is always adjusted then how can you make a precise prediction about it? Once you've done the research and found a post-hoc correlation, what additional tests are needed before making a policy decision, like recommending Paxil for depressed youngsters? If there was outcome switching, is it okay to omit noting that in the paper?