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> In this case, the pharmacokinetics of the two drugs are the same once they hit the bloodstream. Highly incorrect. The amount of the drug and concentration o

> In this case, the pharmacokinetics of the two drugs are the same once they hit the bloodstream. Highly incorrect. The amount of the drug and concentration of the drug and the salt or ester of the drug can impact the pharmacokinetics of the drug. It was used to be thought that morphine and heroin was the same exact thing because the H was converted to morphine quickly. Except H ends up having different metabolites and ratios - not the mention the effects are not the same / even when accounted for the dose and ROA. Also, to the main point, if one produces 10x the effect of the other, the point is the same... Crack is severely more punished over cocaine because it severely impacts user behavior - much more so than cocaine. The campaign to punish crack possession was also largely due to blacks demanding it to be made as so.

chimeracoder 11y ago
> The amount of the drug and concentration of the drug and the salt or ester of the drug can impact the pharmacokinetics of the drug. Can, but in the case of crack cocaine vs. powder cocaine, they demonstrably do not[0][1]. > Crack is severely more punished over cocaine because it severely impacts user behavior - much more so than cocaine It really does not. It can be (but is not always) more habit-forming to smoke a drug than to insufflate it, but this is true of all substances. And intravenous or subcutaneous use of crack cocaine and powder cocaine are literally, 100% identical. > The campaign to punish crack possession was also largely due to blacks demanding it to be made as so. No. There was support from within the black community, but to say it is "largely" due to this is overstating the case. And getting back to the original point, that doesn't actually contradict the original statement, because the reason that black communities felt the impact of violent drug crime and white communities didn't is itself a direct effect of the racial power structures involved. [0] http://www.ncbi.nlm.nih.gov/pubmed/8926741 http://www.ncbi.nlm.nih.gov/pubmed/8926741 [1] https://www.ncbi.nlm.nih.gov/pubmed/8918856 https://www.ncbi.nlm.nih.gov/pubmed/8918856
- powertower 11y ago
  Your references support my statements... "However, evidence exists showing a greater abuse liability, greater propensity for dependence, and more severe consequences when cocaine is smoked (cocaine-base) or injected intravenously (cocaine hydrochloride) compared with intranasal use (cocaine hydrochloride).)." The fact that the effects are different, even with the "same drug". > the reason that black communities felt the impact of violent drug crime and white communities didn't is itself a direct effect of the racial power structures involved. Except no matter where you go in the world, no matter its racial break-down, and no matter what it's history is, the pattern is the same: blacks disproportionately commit violent acts. And when those places are near 100% black, it gets even worse. > And intravenous or subcutaneous use of crack cocaine and powder cocaine are literally, 100% identical. We are comparing powder cocaine insufflated with crack smoked and how that impacted black communities.
  - chimeracoder 11y ago
    > Except no matter where you go in the world, no matter its racial break-down, and no matter what it's history is, the pattern is the same: blacks disproportionately commit violent acts. I wish you'd come out and stated that this was your thesis from the very beginning. I now regret having wasted my time with this conversation.

chimeracoder 11y ago

> The amount of the drug and concentration of the drug and the salt or ester of the drug can impact the pharmacokinetics of the drug. Can, but in the case of crack cocaine vs. powder cocaine, they demonstrably do not[0][1]. > Crack is severely more punished over cocaine because it severely impacts user behavior - much more so than cocaine It really does not. It can be (but is not always) more habit-forming to smoke a drug than to insufflate it, but this is true of all substances. And intravenous or subcutaneous use of crack cocaine and powder cocaine are literally, 100% identical. > The campaign to punish crack possession was also largely due to blacks demanding it to be made as so. No. There was support from within the black community, but to say it is "largely" due to this is overstating the case. And getting back to the original point, that doesn't actually contradict the original statement, because the reason that black communities felt the impact of violent drug crime and white communities didn't is itself a direct effect of the racial power structures involved. [0] http://www.ncbi.nlm.nih.gov/pubmed/8926741 http://www.ncbi.nlm.nih.gov/pubmed/8926741 [1] https://www.ncbi.nlm.nih.gov/pubmed/8918856 https://www.ncbi.nlm.nih.gov/pubmed/8918856

powertower 11y ago
Your references support my statements... "However, evidence exists showing a greater abuse liability, greater propensity for dependence, and more severe consequences when cocaine is smoked (cocaine-base) or injected intravenously (cocaine hydrochloride) compared with intranasal use (cocaine hydrochloride).)." The fact that the effects are different, even with the "same drug". > the reason that black communities felt the impact of violent drug crime and white communities didn't is itself a direct effect of the racial power structures involved. Except no matter where you go in the world, no matter its racial break-down, and no matter what it's history is, the pattern is the same: blacks disproportionately commit violent acts. And when those places are near 100% black, it gets even worse. > And intravenous or subcutaneous use of crack cocaine and powder cocaine are literally, 100% identical. We are comparing powder cocaine insufflated with crack smoked and how that impacted black communities.
- chimeracoder 11y ago
  > Except no matter where you go in the world, no matter its racial break-down, and no matter what it's history is, the pattern is the same: blacks disproportionately commit violent acts. I wish you'd come out and stated that this was your thesis from the very beginning. I now regret having wasted my time with this conversation.