Are you seriously comparing an FDA trial to a 17th century trial? If you don't see the absurdity of trying to equate the quality of those two I don't know what

Are you seriously comparing an FDA trial to a 17th century trial? If you don't see the absurdity of trying to equate the quality of those two I don't know what to tell you, setting aside your idea that a "26.7" sample size would be anywhere near significant enough to draw any sort of meaningful conclusion.