4 ms·

MRSA superbug's resistance to antibiotics is broken

52 points by CarolineW 11y ago

pygy_ 11y ago
... in mice.
- lettergram 11y ago
  Most antibiotics work on one mamial all mamials, this isnt always the case, but usually. That being said, tests are done on mice to see if it causes harm, as they have a quick turn over rate. Then they usually move to other animals with a slower aging process, but closer physiology
  - pygy_ 11y ago
    I was on mobile and had little time. This doesn't address biodisponibility and toxicity in humans. Both are critical. This may be a breakthrough, but we'll have to wait the results of phase III trials before claiming victory.
bitwize 11y ago
For now.
bborud 11y ago
How is this different from all the other claims of an antibiotic that can deal with MRSA? (Yeah, before sharing this link, I did a quick Google search and skimmed the results and there were claims back to 2014 that various parties have "cracked the superbug".)
- deleted 11y ago
  [deleted]
fjarlq 11y ago
The newscientist.com link is broken for me, due to "Maintenance in Progress". Alternate links: http://arstechnica.com/science/2016/03/sidekick-chemicals-reverse-antibiotic-resistance-in-microbes/ http://arstechnica.com/science/2016/03/sidekick-chemicals-re... https://www.sciencenews.org/article/molecules-found-counter-antibiotic-resistance https://www.sciencenews.org/article/molecules-found-counter-...
- CarolineW 11y ago
  It was also down for me for a short time, but seems to be back again.
dmichulke 11y ago
Hospitals are like evolutionary pressure chambers and any drug that combats MRSA will inevitably lead to its own demise. The more accessible and effective the drug is, the less time it will buy us.
bmh_ca 11y ago
MRSA is an arms race. It will just evolve a resistance to this new technique. The only solution I've heard anything about that "beats" MRSA is the Norway solution: http://www.drweil.com/drw/u/QAA400703/Has-Norway-Beaten-MRSA.html http://www.drweil.com/drw/u/QAA400703/Has-Norway-Beaten-MRSA... That's dated, so I'd be interested in hearing what the stats on the effectiveness of their approach are now. EDIT: It's worth noting that the two philosophies appear to be in stark contrast. The Norway tact is to drastically reduce drug prescription. The American tact is to create more drugs.
nikolay 11y ago
I hope we learn from our mistake to abuse A-bombs (antibiotics) in medicine. There's way more damage from the abuse than just MRSA!

52 points by CarolineW 11y ago

pygy_ 11y ago

... in mice.

lettergram 11y ago
Most antibiotics work on one mamial all mamials, this isnt always the case, but usually. That being said, tests are done on mice to see if it causes harm, as they have a quick turn over rate. Then they usually move to other animals with a slower aging process, but closer physiology
- pygy_ 11y ago
  I was on mobile and had little time. This doesn't address biodisponibility and toxicity in humans. Both are critical. This may be a breakthrough, but we'll have to wait the results of phase III trials before claiming victory.

bitwize 11y ago

For now.

bborud 11y ago

How is this different from all the other claims of an antibiotic that can deal with MRSA? (Yeah, before sharing this link, I did a quick Google search and skimmed the results and there were claims back to 2014 that various parties have "cracked the superbug".)

deleted 11y ago
[deleted]

fjarlq 11y ago

The newscientist.com link is broken for me, due to "Maintenance in Progress". Alternate links: http://arstechnica.com/science/2016/03/sidekick-chemicals-reverse-antibiotic-resistance-in-microbes/ http://arstechnica.com/science/2016/03/sidekick-chemicals-re... https://www.sciencenews.org/article/molecules-found-counter-antibiotic-resistance https://www.sciencenews.org/article/molecules-found-counter-...

CarolineW 11y ago
It was also down for me for a short time, but seems to be back again.

dmichulke 11y ago

Hospitals are like evolutionary pressure chambers and any drug that combats MRSA will inevitably lead to its own demise. The more accessible and effective the drug is, the less time it will buy us.

bmh_ca 11y ago

MRSA is an arms race. It will just evolve a resistance to this new technique. The only solution I've heard anything about that "beats" MRSA is the Norway solution: http://www.drweil.com/drw/u/QAA400703/Has-Norway-Beaten-MRSA.html http://www.drweil.com/drw/u/QAA400703/Has-Norway-Beaten-MRSA... That's dated, so I'd be interested in hearing what the stats on the effectiveness of their approach are now. EDIT: It's worth noting that the two philosophies appear to be in stark contrast. The Norway tact is to drastically reduce drug prescription. The American tact is to create more drugs.

nikolay 11y ago

I hope we learn from our mistake to abuse A-bombs (antibiotics) in medicine. There's way more damage from the abuse than just MRSA!