> Even n > 20 can be difficult for certain studies. For some expensive experiments even n=3 is difficult to reach. "Should we do another replicate and go from

> Even n > 20 can be difficult for certain studies. For some expensive experiments even n=3 is difficult to reach. "Should we do another replicate and go from n=2 to n=3, or should we hire another post-doc?" is a relatively common (rhetorical) question.