It is absolutely way too high. Here's a paper that puts it at about 1 per 13,000: Lagasse (2002): http://student.purduecal.edu/~jbojczuk/Research/Anesthesia%20S

It is absolutely way too high. Here's a paper that puts it at about 1 per 13,000: Lagasse (2002): http://student.purduecal.edu/~jbojczuk/Research/Anesthesia%20Safety%20between%20CRNAs%20supervision.pdf http://student.purduecal.edu/~jbojczuk/Research/Anesthesia%2... It's worth noting that their data contains zero observed deaths in ASA Physical Status I Patients, which are basically healthy adults. I would assume things have either stayed the same or improved: Sevoflurane was just starting to be used around the time that the data were taken for that paper.