5 ms·

Scientists develop very early stage human stem cell lines

69 points by salmonet 11y ago

jawns 11y ago
Kudos to the author for pointing out the distinction between stem cells derived from the destruction of an embryo and stem cells derived from adult tissue, and for explaining which type of stem cells this research involves (embryonic). Too often, even reputable news sites don't properly explain the difference, or even say which of the two they're talking about.
jessriedel 11y ago
Related facts that were new to me: The cells of the placenta correspond genetically to the fetus, not the mother (although it meshes with maternal cells, so that the physical organ contains a layer of maternal cells that intermingle with fetal cells). http://www.nsta.org/publications/news/story.aspx?id=53497 http://www.nsta.org/publications/news/story.aspx?id=53497 The division between placental and non-placental cells is, rather sensibly, the first step of specialization in the developing fetus. https://en.wikipedia.org/wiki/Cell_potency https://en.wikipedia.org/wiki/Cell_potency The chain of increasing specializatio can be broken up like this: > Totipotent (a.k.a. omnipotent) stem cells can differentiate into embryonic and extraembryonic cell types. Such cells can construct a complete, viable organism.[4] These cells are produced from the fusion of an egg and sperm cell. Cells produced by the first few divisions of the fertilized egg are also totipotent.[5] > Pluripotent stem cells are the descendants of totipotent cells and can differentiate into nearly all cells,[4] i.e. cells derived from any of the three germ layers.[6] > Multipotent stem cells can differentiate into a number of cell types, but only those of a closely related family of cells.[4] > Oligopotent stem cells can differentiate into only a few cell types, such as lymphoid or myeloid stem cells.[4] > Unipotent cells can produce only one cell type, their own,[4] but have the property of self-renewal, which distinguishes them from non-stem cells (e.g. progenitor cells, muscle stem cells). https://en.wikipedia.org/wiki/Stem_cell#Potency_definition https://en.wikipedia.org/wiki/Stem_cell#Potency_definition
fourstar 11y ago
Glad to see more focus on breakthroughs in health care. We are living in exciting times, but I just wish that more research authorities would be willing to share clinical trial data with one another or even work together. I suspect most of them are unwilling to do so due to the refusal of patent-sharing (and initial funding costs). How come there isn't a YC for more health related startups/companies (or is there and I just haven't heard of it yet)?

69 points by salmonet 11y ago

jawns 11y ago

Kudos to the author for pointing out the distinction between stem cells derived from the destruction of an embryo and stem cells derived from adult tissue, and for explaining which type of stem cells this research involves (embryonic). Too often, even reputable news sites don't properly explain the difference, or even say which of the two they're talking about.

jessriedel 11y ago

Related facts that were new to me: The cells of the placenta correspond genetically to the fetus, not the mother (although it meshes with maternal cells, so that the physical organ contains a layer of maternal cells that intermingle with fetal cells). http://www.nsta.org/publications/news/story.aspx?id=53497 http://www.nsta.org/publications/news/story.aspx?id=53497 The division between placental and non-placental cells is, rather sensibly, the first step of specialization in the developing fetus. https://en.wikipedia.org/wiki/Cell_potency https://en.wikipedia.org/wiki/Cell_potency The chain of increasing specializatio can be broken up like this: > Totipotent (a.k.a. omnipotent) stem cells can differentiate into embryonic and extraembryonic cell types. Such cells can construct a complete, viable organism.[4] These cells are produced from the fusion of an egg and sperm cell. Cells produced by the first few divisions of the fertilized egg are also totipotent.[5] > Pluripotent stem cells are the descendants of totipotent cells and can differentiate into nearly all cells,[4] i.e. cells derived from any of the three germ layers.[6] > Multipotent stem cells can differentiate into a number of cell types, but only those of a closely related family of cells.[4] > Oligopotent stem cells can differentiate into only a few cell types, such as lymphoid or myeloid stem cells.[4] > Unipotent cells can produce only one cell type, their own,[4] but have the property of self-renewal, which distinguishes them from non-stem cells (e.g. progenitor cells, muscle stem cells). https://en.wikipedia.org/wiki/Stem_cell#Potency_definition https://en.wikipedia.org/wiki/Stem_cell#Potency_definition

fourstar 11y ago

Glad to see more focus on breakthroughs in health care. We are living in exciting times, but I just wish that more research authorities would be willing to share clinical trial data with one another or even work together. I suspect most of them are unwilling to do so due to the refusal of patent-sharing (and initial funding costs). How come there isn't a YC for more health related startups/companies (or is there and I just haven't heard of it yet)?