I live in Boston, and I agree that the climate sucks (I keep telling myself that it builds character). Housing prices are outrageous...for anyone who isn't com

I live in Boston, and I agree that the climate sucks (I keep telling myself that it builds character). Housing prices are outrageous...for anyone who isn't coming from the Bay Area or Manhattan. (If you do move here, rent an apartment and wait for the housing bubble to finish bursting.) But there are a number of tech companies around, either in Cambridge/Somerville or in the Boston suburbs. The public transportation system is decent and the city is compact enough that a lot of things are within a half-hour drive of one another. Regarding biotech, I used to work on the Human Genome Project at what is now the Broad Institute (which got spun off from the Whitehead Institute). Novartis rents a floor or two of the building I work in and owns a whole building a block away. Boston's Museum of Science is a good place to take kids; they have a "Discovery Center" that's specifically oriented towards 0-to-5-year-olds, but my three- and five-year-old have fun at a lot of the other exhibits as well.