Considering that the body regulates its temperature by controlling blood flow to the extremities, maybe it's not surprising that venus blood in particular is no

Considering that the body regulates its temperature by controlling blood flow to the extremities, maybe it's not surprising that venus blood in particular is not homogeneous. As the body cools blood flow to the hands is reduced. Venus blood is also impacted by movement, gravity, etc... Since there's no pulse in the veins, would it not make sense that the heavier constituents of the blood would remain as the lighter components "drain?" I wonder if like how red blood cells would settle to the bottom in a test tube one might expect that there would be differing concentrations of blood constituents in venus blood in the extremities depending on the elevation, temperature, perfusion, etc... of the extremity?