Lior Pachter on read alignment in general is a good start[1]. This package seems to modify the human reference genome based on the known mutations a person h

Lior Pachter on read alignment in general is a good start[1]. This package seems to modify the human reference genome based on the known mutations a person has, making it easier to map an exon back to a genomic position. [1] https://liorpachter.wordpress.com/2015/11/01/what-is-a-read-mapping/ https://liorpachter.wordpress.com/2015/11/01/what-is-a-read-...