"tldr: Want a JIT? Use PyPy." or spend some time helping with Pyjion to add a C API to CPython for plugging in a JIT of your choice - https://github.com/Micro

"tldr: Want a JIT? Use PyPy." or spend some time helping with Pyjion to add a C API to CPython for plugging in a JIT of your choice - https://github.com/Microsoft/Pyjion https://github.com/Microsoft/Pyjion