3 ms·

IndieBio SF’s Second Cohort of Biotech Startups

9 points by cing 11y ago

dnautics 11y ago
My prediction: zero of these companies will be around in five years. Gelzen has the best product and is a nice idea, but the material it's replacing is literally waste material from industrial process. Koniku's claim to be the only chip with neurons is flat out false, I can order assays on a multiplexed chip directly reading out electrical impulses from cultured neurons, been on the market for nearly half a decade now. Myi might have interesting tech, because I trust their cto... But I'm honestly not sure about the other folks involved, in any case diagnostics is going to be very very hard in the next few years.
- cing 11y ago
  How do you feel about the first IndieBio cohort? http://sf.indiebio.co/indiebio-sf-announces-first-class-11-biotech-startups/ http://sf.indiebio.co/indiebio-sf-announces-first-class-11-b...
  - dnautics 11y ago
    Mostly crap, but I like pembient and maybe Clara foods, they have shots at making it. I really want an abiobot but I don't think their founder will make it. Same with arc reactor. Blue turtle was the fraudster of the group. I know enough about Gaucher disease to know that their proposal was total nonsense. I'm not harshing on class 1 - probably even with ycombinator, many classes if not all are "mostly crap". Zero, though, is stunning.
    - mjwaz 11y ago
      I think pembient are going to contribute to increasing poaching, not preventing it.
      - dnautics 11y ago
        Maybe. I can see it going the other way.
      - matthewmarkus 11y ago
        Google Alerts has brought this conversation to my attention. If you haven't read our recent thoughts on the issue, I invite you to do so. You can find them here: https://sosv.com/why-pembient-is-confident-in-synthetic-rhino-horn/ https://sosv.com/why-pembient-is-confident-in-synthetic-rhin... As for IndieBio and the prospects of its class members, I'm sure it is too early to tell. We're flattered, though, to be included in this discussion.
    - mjwaz 11y ago
      I think pembient are going to contribute to increasing poaching, not preventing it.
  - deleted 11y ago
    [deleted]
- xmeson 11y ago
  @dnautics where do I order these chips with neurons giving me patch membrane potentials. I really want one of these chips - a link will do. But it has to come with neurons not two sources and i have to culture them. Again, chips, with deliberate microcircuits in 3D with neurons already on it and its a plug and go. Thanks I think you are really awesome if you give me this link. Otherwise you are full of you know what ... :-).
  - dnautics 11y ago
    http://www.cyprotex.com/toxicology/neurotoxicity/eciphrneuro/ http://www.cyprotex.com/toxicology/neurotoxicity/eciphrneuro... I don't think you can order them, but if you think you're going to be doing computation with neurons, you're an idiot. It'll be overhead like a d-wave, except with zero mathematically validated acceleration instead of maybe making a trip into a small corner of NP. Please read what I wrote carefully, I said I can order assays. This is koniku's primary market (pharma paying for assays), but they're way behind. Without this source of revenue, they won't be competitive.

9 points by cing 11y ago

My prediction: zero of these companies will be around in five years. Gelzen has the best product and is a nice idea, but the material it's replacing is literally waste material from industrial process. Koniku's claim to be the only chip with neurons is flat out false, I can order assays on a multiplexed chip directly reading out electrical impulses from cultured neurons, been on the market for nearly half a decade now. Myi might have interesting tech, because I trust their cto... But I'm honestly not sure about the other folks involved, in any case diagnostics is going to be very very hard in the next few years.

cing 11y ago
How do you feel about the first IndieBio cohort? http://sf.indiebio.co/indiebio-sf-announces-first-class-11-biotech-startups/ http://sf.indiebio.co/indiebio-sf-announces-first-class-11-b...
- dnautics 11y ago
  Mostly crap, but I like pembient and maybe Clara foods, they have shots at making it. I really want an abiobot but I don't think their founder will make it. Same with arc reactor. Blue turtle was the fraudster of the group. I know enough about Gaucher disease to know that their proposal was total nonsense. I'm not harshing on class 1 - probably even with ycombinator, many classes if not all are "mostly crap". Zero, though, is stunning.
  - mjwaz 11y ago
    I think pembient are going to contribute to increasing poaching, not preventing it.
    - dnautics 11y ago
      Maybe. I can see it going the other way.
    - matthewmarkus 11y ago
      Google Alerts has brought this conversation to my attention. If you haven't read our recent thoughts on the issue, I invite you to do so. You can find them here: https://sosv.com/why-pembient-is-confident-in-synthetic-rhino-horn/ https://sosv.com/why-pembient-is-confident-in-synthetic-rhin... As for IndieBio and the prospects of its class members, I'm sure it is too early to tell. We're flattered, though, to be included in this discussion.
  - mjwaz 11y ago
    I think pembient are going to contribute to increasing poaching, not preventing it.
- deleted 11y ago
  [deleted]
xmeson 11y ago
@dnautics where do I order these chips with neurons giving me patch membrane potentials. I really want one of these chips - a link will do. But it has to come with neurons not two sources and i have to culture them. Again, chips, with deliberate microcircuits in 3D with neurons already on it and its a plug and go. Thanks I think you are really awesome if you give me this link. Otherwise you are full of you know what ... :-).
- dnautics 11y ago
  http://www.cyprotex.com/toxicology/neurotoxicity/eciphrneuro/ http://www.cyprotex.com/toxicology/neurotoxicity/eciphrneuro... I don't think you can order them, but if you think you're going to be doing computation with neurons, you're an idiot. It'll be overhead like a d-wave, except with zero mathematically validated acceleration instead of maybe making a trip into a small corner of NP. Please read what I wrote carefully, I said I can order assays. This is koniku's primary market (pharma paying for assays), but they're way behind. Without this source of revenue, they won't be competitive.