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Fat cells are not worn out. When they wear out, they're gone. I guess.
by echaozh 11y ago
Fat cells are not worn out. When they wear out, they're gone. I guess.
- DrScump 11y agoThe cells can remain when the lipid contents are depleted. One feature request of mine is triggering apoptosis for empty fat cells.
- danieltillett 11y agoThis was developed more than 30 years ago by the CISRO here in Australia. What they did is made antibodies against fat cells surface proteins. When injected into an animal the animal lost the fat cells all over their body if injected into a vein and just locally if inject into fat tissue. I don’t know whatever came of the technology, but I always thought it would be very popular if applied to humans.
- DrScump 11y agoWould you please sneak me a case? And maybe a Darrel Lea SF chocolate bar or two? But seriously, if it was viable and productizable, somebody would make a mint. Lipo in a syringe?!
- adrianN 11y agoKilling lots of cells at once is a recipe for trouble. Your body's clean up mechanisms are overwhelmed and you die, basically.
- danieltillett 11y agoThis is true, but you can control this by controlling the dose or using locally.
- DrScump 11y agoWell, sure, that's why people who use decouplers scare me.
- danieltillett 11y agoYes this is what I thought too. I have no idea why it never was developed for humans - the original idea was to use it to make lean meat. Done with monoclonals and careful dose escalation it would be a huge hit.