Depression is a big no (and other "demons"). But for autistic scale - experience of synesthesia is on the opposite edge. http://www.wired.com/2014/10/magic-mus

Depression is a big no (and other "demons"). But for autistic scale - experience of synesthesia is on the opposite edge. http://www.wired.com/2014/10/magic-mushroom-brain/ http://www.wired.com/2014/10/magic-mushroom-brain/ Though, the "lack of control" needs to be addressed before starting adventure. I agree that "hacking one's brain" is not for everyone, and its better to be safe than sorry.