A good resource on Ketamine is Erowid's Ketamine vault: https://www.erowid.org/chemicals/ketamine/ https://www.erowid.org/chemicals/ketamine/ The list of Ketam

A good resource on Ketamine is Erowid's Ketamine vault: https://www.erowid.org/chemicals/ketamine/ https://www.erowid.org/chemicals/ketamine/ The list of Ketamine related publications at https://www.erowid.org/references/refs.php?S=ketamine https://www.erowid.org/references/refs.php?S=ketamine lists the first study on effects on depression as from 2000 (just a quick Ctrl-F search, their might be earlier studies).