5 ms·
> Its relief is temporary. Clinical trials at NIMH have found that relapse usually occurs about a week after a single infusion." It then goes on to talk about p
by chimeracoder 11y ago
> Its relief is temporary. Clinical trials at NIMH have found that relapse usually occurs about a week after a single infusion." It then goes on to talk about possibly alleviating this with booster treatments.
I know some people will naturally object to this, but to be honest - assuming people don't build up a tolerance to the effects[0], what's wrong with that?
People are accustomed to taking all sorts of drugs on a daily basis, from antidepressants to sleeping aids to coffee (caffeine!). If someone invented from scratch an antidepressant that could only be taken once a week, we'd be heralding it as a miracle drug.
The main opposition to Ketamine is likely to be its history of recreational use ("Special K"). But that narrative - opposing medicine because of its potential psychoactive effects - is nothing new.
[0] I don't mean a tolerance to Ketamine in general, but a tolerance to this anti-depressive effect
- arthur_pryor 11y agoif anything, for people who are trying to be functional, you'd want to gain tolerance to the recreational effects, but not the anti-depressant effects. tolerance to both seems more likely, but hopefully tolerance to the former outpaces the latter.
- rincebrain 11y agoThe basic problem is that it requires IV infusion, not oral or nasal administration (trials of the latter have issues with consistent dosage, AIUI), and that requires trips to a doctor to do, weekly.