I can't speak to running Clojure outside the JVM, but on the JVM there's good interop with native Java, which allows using Java-based tools and libraries. This

I can't speak to running Clojure outside the JVM, but on the JVM there's good interop with native Java, which allows using Java-based tools and libraries. This instantly gives you access to a whole ecosystem of stuff written for Java. It's very easy to use the Java AWS SDK directly from Clojure code, for example.