Great question. In almost all cases, you have an actionable lead after doing a screen experiment. The problem is typically that you have learned too many, not t

Great question. In almost all cases, you have an actionable lead after doing a screen experiment. The problem is typically that you have learned too many, not too few things. And those things need to be backed with more experimental evidence. But more generally, the iteration latency is about a week to order & receive reagents for another targeted screen. Or if you want to do a single gene CRISPR experiment, you can get the single oligo reagents the next day. Then the cloning, virus production, cell infection, etc. will be about another week if you are rushing. We in genomics are still a far cry from the iteration latency in software dev, but given that many of our scientific forefathers/mothers in the previous generation counted on making a whole genetically engineered mouse (which could take a year+) for an experiment, we're making solid progress. More questions about the real world lab experience are always welcome!