+1 This is a nice reminder about how "organic" this domain is. I agree, even if I read this cover to cover, I wouldn't be ready to nail a bioinformatics job int

+1 This is a nice reminder about how "organic" this domain is. I agree, even if I read this cover to cover, I wouldn't be ready to nail a bioinformatics job interview. As an armchair biologist (among other things,) this paper is a great next-level-of detail from the pop-sci knowledge that "DNA is the Program." Indeed, Wikipedia's illustration of the workings of a ribosome takes steps towards your point, @alexholehouse. It's jagged and sloppy, and while it appears clock-like in its machinations, one must immediately ask how that could be anything but an oversimplification. Is this the workings of the computer that interprets DNA's "program?" https://en.wikipedia.org/wiki/Ribosome#/media/File:Protein_translation.gif https://en.wikipedia.org/wiki/Ribosome#/media/File:Protein_t... A final point, it's sobering to watch this and think that every movement of these proteins represents at least one doctoral thesis' worth of work. Although we have amazing ways of seeing these microscopic actions at play, we don't exactly have debuggers, REPLs or profilers that let us observe cells unaffected. Messy stuff.