Well, sure, because one is before the "and", and one is after it. Not the difference you meant? There are all kinds of differences, but kids usually learn to

Well, sure, because one is before the "and", and one is after it. Not the difference you meant? There are all kinds of differences, but kids usually learn to mostly ignore casing (in English) for meaning when learning to read, and programming makes them unlearn that rule. There are three exceptions (that I think of offhand): starting a sentence, trademarks and acronyms, and proper nouns. The first two don't usually change the meaning much or at all, and the last is pretty much Python's class/instance rule (except reversed).