4 ms·
For better or worse, 'connectome' is a legit term used in the field. It's relatively newish (quickly skimming the literature, first mention was in a 2005 artic
by polyfractal 11y ago
For better or worse, 'connectome' is a legit term used in the field. It's relatively newish (quickly skimming the literature, first mention was in a 2005 article). It follows the naming convention setup by 'genome', and includes many variants:
- genome (set of dna material in a cell)
- exome (set of exonic dna material)
- transcriptome (set of all messenger RNA)
- proteome (set of proteins in a cell)
- interactome (set of all interactions in a cell -- protein, small molecular, etc)
- metabolome (set of all small molecular compounds / interactions in a sample)
- connectome (set of all connections in the brain -- e.g. a wiring diagram)
etc etc
- SapphireSun 11y agoWhile we're all on the same team, there's also a distinction in the functional connectome (often as determined by fMRI) vs the structural one (determined by viral tracers and electron microscopy). Of course the goal is to see how the two relate. The one described in the article is functional.
- auvrw 11y agoYep, it is, and "functional" means undirected in this context, as contrasted w/ "effective" or directed. These graphs are often defined by stats like Granger causality as well as some partition of the brain. There's a Prof. named Sporns who has a lot to say about this.