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It's funny that this should appear on HN ... Sunday I just completed a bit of software that looks for candidate CRISPR sites in a particular mouse genome for my
by smoyer 11y ago
It's funny that this should appear on HN ... Sunday I just completed a bit of software that looks for candidate CRISPR sites in a particular mouse genome for my daughter. In our case, the real trick is to find repeats in the section of the chromosome she wants to manipulate that don't also exist in the rest of the chromosome - or any of the other chromosomes.
Like any "big data" project, the trick is representing your data in a way that makes searching it trivial as well as parallelizable.
- junto 11y agoThat sounds like a very interesting and I'm assuming, a sad story. Do you mind if I ask if you are sharing it publicly?
- smoyer 11y agoIt took me a few rereads of my original post to realize what might be sad about it ... then I got it. It's actually a happy story (for me). My daughter is a PhD candidate at the Johns Hopkins school of medicine and is working towards becoming a researcher (molecular genetics). I'm not sure I should comment on which lab she's working in or what they're trying to accomplish. It might not be fun for the mouse but I'm thankful for projects like this because we get to work on something together. It's almost like going back to when she was a girl doing a science project in elementary school.