I'd be worried about general rough-lifestyle stuff affecting your brain's health as well. It is ultimately also a physical organ. Also, being unhealthy is not p

I'd be worried about general rough-lifestyle stuff affecting your brain's health as well. It is ultimately also a physical organ. Also, being unhealthy is not pleasant in general for many people. Another approach might be to just slowly increase enjoyable risky behavior that's more or less all or nothing in its bad effects: driving fast, base jumping, motorcycle riding, helicopter piloting...