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And to add to the confusion, you have another study considering the opposite conclusion. The study explored the effects of exercise increasing free radicals an
by jasode 11y ago
And to add to the confusion, you have another study considering the opposite conclusion. The study explored the effects of exercise increasing free radicals and advanced aging.
http://www.ncbi.nlm.nih.gov/pubmed/9177582 http://www.ncbi.nlm.nih.gov/pubmed/9177582
- outlace 11y agoThis study sort of makes an assumption that increased free radicals causes (at least in part) aging (free radical theory of aging). The relationship between radical oxygen species (free radicals) and aging is not at all clear to my understanding. (this paper is from 1997) Moreover, it's possible that the tissues most susceptible to oxidative stress during exercise (i.e. muscle) are also most adapted to handle it. So overall, yes ROS increase but mostly just in muscle where it is well-adapted to handle it, and the benefits of exercise (lowering blood pressure, better circulation, etc) trump any detriments of increased ROS. Edit: Found this review [ http://www.ncbi.nlm.nih.gov/pubmed/23434764 http://www.ncbi.nlm.nih.gov/pubmed/23434764 ] that considers evidence that ROS may actually be a part of a pro-survival signal cascade
- mikkom 11y agoThis also very related and just released. This was published in quite many local (finnish) newspapers as this is a joint project of Jyväskylä (finnish) and Michican universities. http://www.nature.com/articles/srep18259 http://www.nature.com/articles/srep18259