Load balancers - sure. It just provides a regular, signed x509 certificate that you can use for anything that supports TLS. The auto-configuration client might

Load balancers - sure. It just provides a regular, signed x509 certificate that you can use for anything that supports TLS. The auto-configuration client might not support a specific load balancer, but it's not too hard to request one manually. Many subdomains - well, they don't support wildcard certs so that makes it harder. You can generate one cert with many subdomains, but that still requires extra effort whenever you add one. And it pretty much rules out set ups requiring wildcard subdomains, for instance sites like Deviantart or Tumblr where each user gets their own subdomain.