Ketamine, unaltered, would probably never a good treatment for depression except in some extreme cases. I think people are more interested in understanding how

Ketamine, unaltered, would probably never a good treatment for depression except in some extreme cases. I think people are more interested in understanding how Ketamine can have this unexpected effect so that they can develop classes of drugs that are designed from the ground-up to treat depression. Kind of like how understanding how MAOIs led to tricyclics and then SSRIs. I think that's the direction research is going in.