The big company might well have better quality control (though, depending on the regulatory environment, you may have very good grounds to believe that everyone

The big company might well have better quality control (though, depending on the regulatory environment, you may have very good grounds to believe that everyone's quality control is good enough) -- but it seems unlikely that the same big company has better quality control for one product than for another identical product in different packaging. But not impossible. You could imagine that they do some kind of tests on their pills, and put the "better" batches in the fancier packaging with the higher prices. I doubt it, though. (Though I bet such things do happen in other less tightly regulated markets.)