3 ms·

I'm not clear if you are being sarcastic, but note the GRAS (generally recognized as safe), for ingestion at least...

mrob 11y ago
If you ever stand near a typical vaper, you'll notice they use very high concentrations of flavoring. Any food with this much flavoring would probably be considered inedible. I think very strong flavoring is popular to overcome desensitization caused by frequent use.
binarymax 11y ago
I am not being sarcastic. That entry hasn't changed in the FR since 1983. "Generally recognized as safe" is out of date and the chemical needs another regulatory review and update.
- daveguy 11y ago
  FR is a log of all regulations and you are referencing an old GRAS notification. GRAS is valid and up to date FOR INGESTION ONLY. Here is the most current information on GRAS food additives (not pharma additives) from the FDA: http://www.fda.gov/Food/IngredientsPackagingLabeling/GRAS/ http://www.fda.gov/Food/IngredientsPackagingLabeling/GRAS/ Here is the inactive ingredients database for approved pharmaceutical additives which depends on route of administration: http://www.accessdata.fda.gov/scripts/cder/iig/index.Cfm http://www.accessdata.fda.gov/scripts/cder/iig/index.Cfm
daveguy 11y ago
GRAS is a food additive designation and does apply ONLY to ingestion. The pharmacology of an inhaled substance can be completely different than that of an ingested one. The same goes for intravenous, topical and subcutaneous as well. Just because something is safe for one method of delivery does not mean it is safe for another. GRAS is applicable and continually updated regarding ingestion, but it does NOT apply to inhalation. Edit: side note, the database of additives approved in pharmaceutical products is specific to route of delivery and ,for the US, can be found in the FDA's inactive ingredients database: http://www.accessdata.fda.gov/scripts/cder/iig/index.Cfm http://www.accessdata.fda.gov/scripts/cder/iig/index.Cfm
Lawtonfogle 11y ago
If it is added to a food that is heated, isn't there still a risk for inhalation? Or even if the food isn't heated, a flavor that isn't one of the main (sweet, salty, bitter, sour, umami) isn't actually a flavor. It is a smell. So the only reason it is added to foods is to be inhaled.

mrob 11y ago

If you ever stand near a typical vaper, you'll notice they use very high concentrations of flavoring. Any food with this much flavoring would probably be considered inedible. I think very strong flavoring is popular to overcome desensitization caused by frequent use.

binarymax 11y ago

I am not being sarcastic. That entry hasn't changed in the FR since 1983. "Generally recognized as safe" is out of date and the chemical needs another regulatory review and update.

daveguy 11y ago
FR is a log of all regulations and you are referencing an old GRAS notification. GRAS is valid and up to date FOR INGESTION ONLY. Here is the most current information on GRAS food additives (not pharma additives) from the FDA: http://www.fda.gov/Food/IngredientsPackagingLabeling/GRAS/ http://www.fda.gov/Food/IngredientsPackagingLabeling/GRAS/ Here is the inactive ingredients database for approved pharmaceutical additives which depends on route of administration: http://www.accessdata.fda.gov/scripts/cder/iig/index.Cfm http://www.accessdata.fda.gov/scripts/cder/iig/index.Cfm

daveguy 11y ago

GRAS is a food additive designation and does apply ONLY to ingestion. The pharmacology of an inhaled substance can be completely different than that of an ingested one. The same goes for intravenous, topical and subcutaneous as well. Just because something is safe for one method of delivery does not mean it is safe for another. GRAS is applicable and continually updated regarding ingestion, but it does NOT apply to inhalation. Edit: side note, the database of additives approved in pharmaceutical products is specific to route of delivery and ,for the US, can be found in the FDA's inactive ingredients database: http://www.accessdata.fda.gov/scripts/cder/iig/index.Cfm http://www.accessdata.fda.gov/scripts/cder/iig/index.Cfm

Lawtonfogle 11y ago

If it is added to a food that is heated, isn't there still a risk for inhalation? Or even if the food isn't heated, a flavor that isn't one of the main (sweet, salty, bitter, sour, umami) isn't actually a flavor. It is a smell. So the only reason it is added to foods is to be inhaled.