3 ms·

Re: fecal transplants, do you mean the study with N=46 in which FMT scored a 91% cure rate, 28% higher than placebo? http://www.hcplive.com/conference-coverage/

by gamache 11y ago

Re: fecal transplants, do you mean the study with N=46 in which FMT scored a 91% cure rate, 28% higher than placebo? http://www.hcplive.com/conference-coverage/acg-2015/fmt-passes-first-randomized-placebo-controlled-trial-for-treating-c-dif-infection http://www.hcplive.com/conference-coverage/acg-2015/fmt-pass... Citations needed.

cpncrunch 11y ago
That was one study. There have been a total of 2 placebo-controlled trials into fecal transplants for C.Diff AFAIK. One showed some benefit over placebo, and the other showed no difference. It looks like that link you posted has just cherry-picked the good result. https://news.ycombinator.com/item?id=10679067 https://news.ycombinator.com/item?id=10679067
- gamache 11y ago
  Post links. The one I posted was the most recent I found (October 2015), but most studies I saw (every one I checked, N > 5) reported distinct success for FMT in their abstracts. [EDIT] You've posted a link now, and the article is behind a paywall. There may be a correlation between that and the fact that it didn't get any upvotes, but we'd need sizable trials to be sure. :)
  - cpncrunch 11y ago
    I didn't realise it was a paywall. If you search for "Mixed Results for Fecal Transplant in First Randomized Trial" you'll get through the paywall. I hate paywalls for this reason, but I didn't find any non-paywalled versions of the article -- they all just seem to cherry-pick the good result and completely ignore the other one.