Someone in the comments section of the blog links to an interesting article w.r.t. your first point: http://www.nature.com/news/registered-clinical-trials-make

Someone in the comments section of the blog links to an interesting article w.r.t. your first point: http://www.nature.com/news/registered-clinical-trials-make-positive-findings-vanish-1.18181 http://www.nature.com/news/registered-clinical-trials-make-p... The snark in the original article makes the author sound like a total idiot. But let's not get in the way of HN's Two Minutes Hate?