What kind of job is it? Are you working as part of a team? Does everyone else work remote? If you are working with others the first thing I would personally as

What kind of job is it? Are you working as part of a team? Does everyone else work remote? If you are working with others the first thing I would personally ask is what they use for communication (slack, IRC, e-mail, etc). If you are going to be part of a team where the majority of them work in an office it is very easy to be forgotten about or left out of things depending on what technology they are using and what the culture is. I would also ask what the work hour expectations are and have it documented. Are you expected to be online from say 8am-5pm local time? I have seen some people told "just make sure you get your work done" but then let go because they were not making themselves available during the hours the rest of the team was online (even though their work was getting done). In my experience perception plays a big role in working remotely. If the people in the office don't constantly hear from you or see you online the idea that you are slacking off because nobody is there to manage you starts creeping in. Also don't be afraid to ask for the same type of perks non-remote employees get with regards to hardware/software/etc.