4 ms·
> Re: Malaria, homelessness, HIV, refugees, war, climate change, income inequality, gender inequality, hate crimes. There are tons of informatics needs for mod
by noname123 11y ago
> Re: Malaria, homelessness, HIV, refugees, war, climate change, income inequality, gender inequality, hate crimes.
There are tons of informatics needs for modeling malaria genome evolution specially against emergence of front-line drug resistance that is spreading from SE Asia to Africa. Tools need to be built to inform public health officials where the genome's gene flow is headed next to modify the front-line treatment to contain the spread (e.g., Real-time genomic surveillance of Artesminin resistance of Plasmodium).
There is an entire open-source community of people uploading and sharing time-stamped genomic samples of malaria and host information if you are interested (http://www.malariagen.net/ http://www.malariagen.net/).
Similarly for HIV, there are lots of public health research groups doing modeling of HIV transmission, applied to specific local communities to contain an epidemic. Web front-end needs to be made and data pipelines that crunch incoming input data is needed. Most of this work is done in academic labs where information is only broadcasted on papers but could use a nicer front-end open to public and automated back-end for production data crunching. (e.g., http://web2.research.partners.org/cepac/model.html http://web2.research.partners.org/cepac/model.html).
- magicalist 11y agothat's just stating that there is a need, not where to start :) I wouldn't have any idea on where to go to help out with those either
- noname123 11y ago1) Join a lab as a programmer (e.g., National Weather Service (climate), J. Craig Institute (infectious diseases)) 2) Read the computational papers on a subject you are interested; replicate the results in the papers and open source your software/pipeline; apply the method to a newer data-set. 3) Contribute to a open source informatics toolchain used for the subject (e.g., https://github.com/bigdatagenomics/adam https://github.com/bigdatagenomics/adam)