3 ms·
I'm not too sure about using immunosuppression and gene editing to make organs cross-species transplantable. I'm a fan of the method that washes the pig cells o
by stephengillie 11y ago
I'm not too sure about using immunosuppression and gene editing to make organs cross-species transplantable. I'm a fan of the method that washes the pig cells off the organ's protein scaffold, then takes a few cells from the patient and grows them on the scaffold to make a new native organ. The way described in the article just seems like a less elegant process, is it cheaper or easier in some way?
- dnautics 11y agoCheaper, in the long run. Why bother with that scaffold and seeding and all that when you can just take the organ straight out of the animal. Plus you still have to gm the pig. For example there's an allergen n-glycolyl neuraminic acid which is present in most extracellular matrix proteins that will be in the scaffold.