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Ironically, you're talking about the very thing this article leads with: that Linus Pauling touted vitamin C as a miracle cure with over-dosing, despite no evid
by scott_s 11y ago
Ironically, you're talking about the very thing this article leads with: that Linus Pauling touted vitamin C as a miracle cure with over-dosing, despite no evidence, and none has been found.
(I also think that article lead is irresponsible, because if it turns out this study holds up, and vitamin C is a viable treatment for this kind of cancer, we have soundly shown it does not work in the many areas we have tested it.)
- majkinetor 11y agoNo , we have proof that small insignificant doses do not work. Nobody ever said otherwise.
- scott_s 11y agoWhat do you deem "insignificant"? The required daily dose is about 90 mg. There are experiments which include several grams [1, 2, 3], which is a large enough dose that those writing the papers call it a "megadose". If you consider a megadose to be 1,000g and 10,000g, then I think that's just moving the goal posts. Is there a dosage level at which you would say, "Yes, with no clear signal at that level, it's probable it makes no difference"? [1] http://www.ncbi.nlm.nih.gov/pubmed/11700812?dopt=Abstract http://www.ncbi.nlm.nih.gov/pubmed/11700812?dopt=Abstract [2] http://www.ncbi.nlm.nih.gov/pubmed/23440782 http://www.ncbi.nlm.nih.gov/pubmed/23440782 [3] http://www.ncbi.nlm.nih.gov/pubmed/8191227 http://www.ncbi.nlm.nih.gov/pubmed/8191227, shows some positive evidence, which may be noise, and concludes "needs more research" - despite there already being a lot, with no clear positive signal.