5 ms·

Not at all. I experimented 5+ years with it and took on several occasions 100+g per day with regular input between 10-15g per day. The only problem I had afte

Not at all. I experimented 5+ years with it and took on several occasions 100+g per day with regular input between 10-15g per day. The only problem I had after 5 years is slight pain in esophagus immediately after taking C, but it passed after I switched to taking C on full stomach. Note: you MUST use pure AA powder, nothing else. Timing of C is essential - you must do it right, or the effects are minimal (you basically have to simulate the liver ancestral production now disabled in humans). Vitamin C is a miracle thing IMO, especially 4 kids. My daughter was taking 1g since age 1 (now has 5) and she has remarkable health (she is sick once or twice per year for 2-4 days without any complications with being in kindergarten with 30+ kids since age 1, although the non-vitamin-c factors are contributing to this picture quite a bit). Vitamin C is the most effective virus killer in large doses if you time it right. It is poor antibiotic but you have many options in plant world for that.

mb_72 11y ago
These are fairly typical anecdotal comments made by people pushing Vitamin C cures / treatment, often in conjunction with mention of 'miracles'. Oblig xkcd: https://xkcd.com/1217/ https://xkcd.com/1217/
- majkinetor 11y ago
  What can I say, it works for me and few more people I know. But the argument you are giving is quite pointless - vitamin C has no side effects and it is dead cheap so there is no harm in trying it out for several months and deciding on your own if its good or not for you.
  - mb_72 11y ago
    > What can I say, it works for me and few more people I know. You don't know that - it could have been other unknown factors that made the difference. The same claims of 'working' are made for homoeopathy etc. In general 'trying stuff' is a waste of effort, time and money unless there is supporting evidence for efficacy.
    - majkinetor 11y ago
      You really can never know for sure, vitamin C or whatever. Many many drugs are used in mainstream medicine without clear proof or mechanism of action. If you have a real problem to solve effort and money may be irrelevant. It was for me. I had 5 times a year common cold up until i did vit C thing.
  - kmicklas 11y ago
    > What can I say, it works for me and few more people I know. Worked in what way? You made no mention of what it actually did, except maybe prevent some viral infections?
    - majkinetor 11y ago
      I didnt want to elaborate here, i did so on several other places. It basically stops common cold and probably other common viral diseases in a day if used right. For instance check my protocol here https://www.paleohacks.com/sick/how-do-you-take-care-of-yourself-when-you-have-the-common-cold-9117 https://www.paleohacks.com/sick/how-do-you-take-care-of-your...
  - gabemart 11y ago
    > vitamin C has no side effects I'm not aware of evidence that this is true for megadoses (e.g. 10g per day, as you mentioned). Given that you are making a claim not supported by mainstream medical consensus (that megadoses of vitamin C have positive health effects), you are essentially arguing that megadoses of Vitamin C have a different effect than regular doses. Given that you admit that megadoses have a different effect to regular doses, what is your evidence that megadoses have no side effects?
    - liberale 11y ago
      Toxicity of vit-c is very low. Death by vit-c overdose is un-heard of. Intaking enough vit-c to cause death, could be due to sheer weight of substance intaken rather than bio-chemical function of vit-c. https://en.wikipedia.org/wiki/Vitamin_C#Overdose https://en.wikipedia.org/wiki/Vitamin_C#Overdose Also studies conducted on animals (especially primates) that cannot synthesize vit-c on their own, show that they intake about upto 80x the RDA value of vitamin-c. So, humans intake as low as 1.25% of vit-c levels that monkeys eat. https://en.wikipedia.org/wiki/Vitamin_C#Daily_requirements https://en.wikipedia.org/wiki/Vitamin_C#Daily_requirements Most often than not, RDA values are a joke and should be treated as bare minimum levels to prevent diseases such as scurvy and not as the optimum level. Sub-clinical deficiency in essential vitamins and minerals always happen.
      - majkinetor 11y ago
        Correcrt. Primates take vit. C in grams naturally for example.
        liberale 11y ago
        Do you have any comprehensive resource on timing Vit-C supplements? Also what form of supplement & which brand did you intake? Liposomal vit-c? Do you also have any comprehensive resources that explains if vit-c supplements can affect recovery from lifting weights or general exercise?
        11y ago
  - scott_s 11y ago
    You have not established causation. That is, you and others you know do it; you have a health outcome you are comfortable with; yet you have not established causation between the two.
mrfusion 11y ago
What would help gum disease?
- majkinetor 11y ago
  Vit c, fish oil, coenzime q10, mumio, low carb. All for the best effect.
gilleain 11y ago
> Vitamin C is the most effective virus killer in large doses if you time it right. Which viruses? All viruses? With what mechanism? This is nothing more than molecular fanboyism. Nothing is a panacea.
- majkinetor 11y ago
  Yes, almost all viruses. It boosts immune system which then takes care of the rest. It works 4 some bacteria too , like h. Pylori. 5g pd eliminated infection in 1 study in 30% of patients which is really good result.
muaddirac 11y ago
I would recommend listening to this sometime: http://www.maximumfun.org/sawbones/sawbones-vitamins http://www.maximumfun.org/sawbones/sawbones-vitamins I'd be curious to see if you still hold the same opinions. (It's a very entertaining podcast too!)
- majkinetor 11y ago
  Dude....
scott_s 11y ago
Ironically, you're talking about the very thing this article leads with: that Linus Pauling touted vitamin C as a miracle cure with over-dosing, despite no evidence, and none has been found. (I also think that article lead is irresponsible, because if it turns out this study holds up, and vitamin C is a viable treatment for this kind of cancer, we have soundly shown it does not work in the many areas we have tested it.)
- majkinetor 11y ago
  No , we have proof that small insignificant doses do not work. Nobody ever said otherwise.
  - scott_s 11y ago
    What do you deem "insignificant"? The required daily dose is about 90 mg. There are experiments which include several grams [1, 2, 3], which is a large enough dose that those writing the papers call it a "megadose". If you consider a megadose to be 1,000g and 10,000g, then I think that's just moving the goal posts. Is there a dosage level at which you would say, "Yes, with no clear signal at that level, it's probable it makes no difference"? [1] http://www.ncbi.nlm.nih.gov/pubmed/11700812?dopt=Abstract http://www.ncbi.nlm.nih.gov/pubmed/11700812?dopt=Abstract [2] http://www.ncbi.nlm.nih.gov/pubmed/23440782 http://www.ncbi.nlm.nih.gov/pubmed/23440782 [3] http://www.ncbi.nlm.nih.gov/pubmed/8191227 http://www.ncbi.nlm.nih.gov/pubmed/8191227, shows some positive evidence, which may be noise, and concludes "needs more research" - despite there already being a lot, with no clear positive signal.

mb_72 11y ago

These are fairly typical anecdotal comments made by people pushing Vitamin C cures / treatment, often in conjunction with mention of 'miracles'. Oblig xkcd: https://xkcd.com/1217/ https://xkcd.com/1217/

majkinetor 11y ago
What can I say, it works for me and few more people I know. But the argument you are giving is quite pointless - vitamin C has no side effects and it is dead cheap so there is no harm in trying it out for several months and deciding on your own if its good or not for you.
- mb_72 11y ago
  > What can I say, it works for me and few more people I know. You don't know that - it could have been other unknown factors that made the difference. The same claims of 'working' are made for homoeopathy etc. In general 'trying stuff' is a waste of effort, time and money unless there is supporting evidence for efficacy.
  - majkinetor 11y ago
    You really can never know for sure, vitamin C or whatever. Many many drugs are used in mainstream medicine without clear proof or mechanism of action. If you have a real problem to solve effort and money may be irrelevant. It was for me. I had 5 times a year common cold up until i did vit C thing.
- kmicklas 11y ago
  > What can I say, it works for me and few more people I know. Worked in what way? You made no mention of what it actually did, except maybe prevent some viral infections?
  - majkinetor 11y ago
    I didnt want to elaborate here, i did so on several other places. It basically stops common cold and probably other common viral diseases in a day if used right. For instance check my protocol here https://www.paleohacks.com/sick/how-do-you-take-care-of-yourself-when-you-have-the-common-cold-9117 https://www.paleohacks.com/sick/how-do-you-take-care-of-your...
- gabemart 11y ago
  > vitamin C has no side effects I'm not aware of evidence that this is true for megadoses (e.g. 10g per day, as you mentioned). Given that you are making a claim not supported by mainstream medical consensus (that megadoses of vitamin C have positive health effects), you are essentially arguing that megadoses of Vitamin C have a different effect than regular doses. Given that you admit that megadoses have a different effect to regular doses, what is your evidence that megadoses have no side effects?
  - liberale 11y ago
    Toxicity of vit-c is very low. Death by vit-c overdose is un-heard of. Intaking enough vit-c to cause death, could be due to sheer weight of substance intaken rather than bio-chemical function of vit-c. https://en.wikipedia.org/wiki/Vitamin_C#Overdose https://en.wikipedia.org/wiki/Vitamin_C#Overdose Also studies conducted on animals (especially primates) that cannot synthesize vit-c on their own, show that they intake about upto 80x the RDA value of vitamin-c. So, humans intake as low as 1.25% of vit-c levels that monkeys eat. https://en.wikipedia.org/wiki/Vitamin_C#Daily_requirements https://en.wikipedia.org/wiki/Vitamin_C#Daily_requirements Most often than not, RDA values are a joke and should be treated as bare minimum levels to prevent diseases such as scurvy and not as the optimum level. Sub-clinical deficiency in essential vitamins and minerals always happen.
    - majkinetor 11y ago
      Correcrt. Primates take vit. C in grams naturally for example.
      - liberale 11y ago
        Do you have any comprehensive resource on timing Vit-C supplements? Also what form of supplement & which brand did you intake? Liposomal vit-c? Do you also have any comprehensive resources that explains if vit-c supplements can affect recovery from lifting weights or general exercise?
        11y ago
- scott_s 11y ago
  You have not established causation. That is, you and others you know do it; you have a health outcome you are comfortable with; yet you have not established causation between the two.

mrfusion 11y ago

What would help gum disease?

majkinetor 11y ago
Vit c, fish oil, coenzime q10, mumio, low carb. All for the best effect.

gilleain 11y ago

> Vitamin C is the most effective virus killer in large doses if you time it right. Which viruses? All viruses? With what mechanism? This is nothing more than molecular fanboyism. Nothing is a panacea.

majkinetor 11y ago
Yes, almost all viruses. It boosts immune system which then takes care of the rest. It works 4 some bacteria too , like h. Pylori. 5g pd eliminated infection in 1 study in 30% of patients which is really good result.

muaddirac 11y ago

I would recommend listening to this sometime: http://www.maximumfun.org/sawbones/sawbones-vitamins http://www.maximumfun.org/sawbones/sawbones-vitamins I'd be curious to see if you still hold the same opinions. (It's a very entertaining podcast too!)

majkinetor 11y ago
Dude....

scott_s 11y ago

Ironically, you're talking about the very thing this article leads with: that Linus Pauling touted vitamin C as a miracle cure with over-dosing, despite no evidence, and none has been found. (I also think that article lead is irresponsible, because if it turns out this study holds up, and vitamin C is a viable treatment for this kind of cancer, we have soundly shown it does not work in the many areas we have tested it.)

majkinetor 11y ago
No , we have proof that small insignificant doses do not work. Nobody ever said otherwise.
- scott_s 11y ago
  What do you deem "insignificant"? The required daily dose is about 90 mg. There are experiments which include several grams [1, 2, 3], which is a large enough dose that those writing the papers call it a "megadose". If you consider a megadose to be 1,000g and 10,000g, then I think that's just moving the goal posts. Is there a dosage level at which you would say, "Yes, with no clear signal at that level, it's probable it makes no difference"? [1] http://www.ncbi.nlm.nih.gov/pubmed/11700812?dopt=Abstract http://www.ncbi.nlm.nih.gov/pubmed/11700812?dopt=Abstract [2] http://www.ncbi.nlm.nih.gov/pubmed/23440782 http://www.ncbi.nlm.nih.gov/pubmed/23440782 [3] http://www.ncbi.nlm.nih.gov/pubmed/8191227 http://www.ncbi.nlm.nih.gov/pubmed/8191227, shows some positive evidence, which may be noise, and concludes "needs more research" - despite there already being a lot, with no clear positive signal.