Right - but we used to struggle with the output of the last generation of sequencers too. Computing capacity and storage have scaled at about the same rate. Or

Right - but we used to struggle with the output of the last generation of sequencers too. Computing capacity and storage have scaled at about the same rate. Or perhaps it's more accurate to say that the costs have come down, so we can throw more iron at the problem - these are embarrassingly parallel problems... As an example, the last sequencing analysis cluster I setup (~2010) ran with 2x bonded gigabit networks between our compute nodes and storage and had 10TB of network storage. The newest one is running 10GigE, has 200+TB of storage, and is cheaper. And we are a small shop in this field.