This is absolutely true. I've done differential expression analysis on many RNA-seq and microarray datasets, and despite the fact that the basic pipeline for su

This is absolutely true. I've done differential expression analysis on many RNA-seq and microarray datasets, and despite the fact that the basic pipeline for such analysis is quite straightforward and easily automated, every analysis is asking different biological questions and has different confounding factors that need to be addressed, so the analysis of each dataset ends up being quite different from all the others.