3 ms·
How can they prevent this virus from evolving to replicate in non-cancerous cells? I wonder if that's why they started with a benign virus like herpes. Very co
by jjbiotech 11y ago
How can they prevent this virus from evolving to replicate in non-cancerous cells? I wonder if that's why they started with a benign virus like herpes.
Very cool, but slightly scarey at the same time.
- csbrooks 11y agoReminds me of the start of the movie I am Legend...
- maxerickson 11y agoThey are using poliovirus here: http://www.cancer.duke.edu/btc/modules/research3/index.php?id=41 http://www.cancer.duke.edu/btc/modules/research3/index.php?i... They did investigate the genetic stability of their engineered virus: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881183/ http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2881183/
- zmanian 11y agoI think it is simultaneously amazing and scary that the FDA is starting to approve self replicating organisms in therapies. Bacteriophages are a promising replacement for antibiotics. I wonder if they can follow a similar regulatory path.
- QuercusMax 11y agoLive-virus vaccines are already a thing; in some sense this is just a new application of them as far as the FDA is concerned.
- tsotha 11y agoI'm not sure I would call herpes a benign virus. There are strains that will kill you.