3 ms·
That's fair, but if you don't already present with a disease, I don't know how much WES can tell you. At least with a SNP chip, and the correct analysis, you ca
by coetzeesg 11y ago
That's fair, but if you don't already present with a disease, I don't know how much WES can tell you. At least with a SNP chip, and the correct analysis, you can start speculating about what may happen down the road.
- adenadel 11y agoI agree completely. The nice thing about the exome is that the knowledge is more extensible than the SNP chip. If we discover new variants within the exome you won't need to be genotyped a second time. That logic probably argues more for WGS though. It is also the problem with WGS and WES. You get a ton of variants of unknown significance that the patient/customer will be curious about but be able to obtain no answers.