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I hope this means we can finally upgrade our results to the latest chip, or that they restore some of the SNPs they dropped in the later chips that make these r

I hope this means we can finally upgrade our results to the latest chip, or that they restore some of the SNPs they dropped in the later chips that make these reports impossible to compute. I've been waiting to unlock the Alzheimer's results for ages, but it always tells me that "upgrading to the latest platform is unavailable".

berberous 11y ago
I could be wrong, but I think you can still export your raw genetic data, right? If so, have you checked out Promethease? I have not used it in a while, but I imagine it will tell you most if not all of what 23andMe would have on Alzheimer's (and quite possibly more). http://www.snpedia.com/index.php/Promethease http://www.snpedia.com/index.php/Promethease https://promethease.com/ https://promethease.com/
csl 11y ago
I've made a 23andMe parser that can report on this. Actually, it covers quite a lot of their health results: https://github.com/cslarsen/dna-traits https://github.com/cslarsen/dna-traits The test for Alzheimers is here: https://github.com/cslarsen/dna-traits/blob/master/py-dnatraits/dna_traits/health.py#L17 https://github.com/cslarsen/dna-traits/blob/master/py-dnatra... (the algorithm used to be patented, by the way). By closely reading the algorithm, you can probably find out yourself, given that 23andMe still lets you browse your genome. To see all health reports, run this file on the downloaded genome: https://github.com/cslarsen/dna-traits/blob/master/py-dnatraits/bin/health-risks.py https://github.com/cslarsen/dna-traits/blob/master/py-dnatra... (you have to compile the C++ code first) Actually was playing with the idea of monetizing off this project, but the laws in my country prohibit me from doing so. In fact, just using the program I made is illegal unless its my own genome.
- farresito 11y ago
  Woah. Quite interesting! Thank you. I've been increasingly interested in bioinformatics and your project seems quite nice. I will definitely give it a try.
  - csl 11y ago
    Thanks. It's definitely a lot of fun. And, as you can see, some things are not hard at all to detect. In fact, I was surprised how little knowledge you need to be able to flick through genome wide association studies (GWAS) and casually play around with their findings. (It's also fun to see how desperately some GWAS studies seem to try to make sense of the genome --- it's a pretty young field, I guess!) Of course, you should be pretty careful with interpreting results as a hobbyist (as I am). But probing your genome with a parser, like the one I've made, is a great vehicle for piquing your intellectual curiosity.

berberous 11y ago

I could be wrong, but I think you can still export your raw genetic data, right? If so, have you checked out Promethease? I have not used it in a while, but I imagine it will tell you most if not all of what 23andMe would have on Alzheimer's (and quite possibly more). http://www.snpedia.com/index.php/Promethease http://www.snpedia.com/index.php/Promethease https://promethease.com/ https://promethease.com/

csl 11y ago

I've made a 23andMe parser that can report on this. Actually, it covers quite a lot of their health results: https://github.com/cslarsen/dna-traits https://github.com/cslarsen/dna-traits The test for Alzheimers is here: https://github.com/cslarsen/dna-traits/blob/master/py-dnatraits/dna_traits/health.py#L17 https://github.com/cslarsen/dna-traits/blob/master/py-dnatra... (the algorithm used to be patented, by the way). By closely reading the algorithm, you can probably find out yourself, given that 23andMe still lets you browse your genome. To see all health reports, run this file on the downloaded genome: https://github.com/cslarsen/dna-traits/blob/master/py-dnatraits/bin/health-risks.py https://github.com/cslarsen/dna-traits/blob/master/py-dnatra... (you have to compile the C++ code first) Actually was playing with the idea of monetizing off this project, but the laws in my country prohibit me from doing so. In fact, just using the program I made is illegal unless its my own genome.

farresito 11y ago
Woah. Quite interesting! Thank you. I've been increasingly interested in bioinformatics and your project seems quite nice. I will definitely give it a try.
- csl 11y ago
  Thanks. It's definitely a lot of fun. And, as you can see, some things are not hard at all to detect. In fact, I was surprised how little knowledge you need to be able to flick through genome wide association studies (GWAS) and casually play around with their findings. (It's also fun to see how desperately some GWAS studies seem to try to make sense of the genome --- it's a pretty young field, I guess!) Of course, you should be pretty careful with interpreting results as a hobbyist (as I am). But probing your genome with a parser, like the one I've made, is a great vehicle for piquing your intellectual curiosity.