3 ms·
> Your cells dividing indefinitely is not the opposite of aging, it's cancer. Look at it this way: the Hayflick Limit on cellular replication limits act as a f
by rewqfdsa 11y ago
> Your cells dividing indefinitely is not the opposite of aging, it's cancer.
Look at it this way: the Hayflick Limit on cellular replication limits act as a fail-safe in case other growth inhibition mechanisms fail. If a liver cell decides that it wants to be its own immortal organism but doesn't express telomerase, it won't get very far in its enterprise. The replication limit makes it more likely that we'll survive to reproductive age.
On the other hand, the Hayflick Limit kills us. Evolution doesn't care much about this side effect, but we do. If we can suppress cancer other ways --- or hell, even if we can't --- NOPing out the Hayflick Limit safety code is worthwhile.