3 ms·
Malaria protein could be an effective weapon against cancer
- jobu 11y agoThe full text of the study is paywalled here: http://www.cell.com/cancer-cell/abstract/S1535-6108%2815%2900334-7 http://www.cell.com/cancer-cell/abstract/S1535-6108%2815%290... Fortunately the summary there has some useful information: "rVAR2 (recombinant malarial protein VAR2CSA) fused to diphtheria toxin or conjugated to hemiasterlin compounds strongly inhibits in vivo tumor cell growth and metastasis" Anyone know how they're attaching those toxins/compounds to the malarial protein?
- trhway 11y ago>how they're attaching those toxins/compounds to the malarial protein? curious for the same, googled "protein fused to toxin" and it brought like this https://en.wikipedia.org/wiki/Immunotoxin https://en.wikipedia.org/wiki/Immunotoxin and http://www.ncbi.nlm.nih.gov/pubmed/8105849 http://www.ncbi.nlm.nih.gov/pubmed/8105849
- louthy 11y agoOdd, I posted this exact link yesterday[1]. I always thought there was link normalisation on HN? [1] https://news.ycombinator.com/item?id=10390791 https://news.ycombinator.com/item?id=10390791