4 ms·
A comprehensive test looking at the BRCAs may deeply sequence sequence the entire gene(s); spanning around 150 thousand base pairs. You'd not only want to look
by ihodes 11y ago
A comprehensive test looking at the BRCAs may deeply sequence sequence the entire gene(s); spanning around 150 thousand base pairs. You'd not only want to look for SNPs, but novel SNVs, and various structural variants (SVs) and copy-number variants (CNVs). I don't know the most common class of mutations for BRCA1 and 2, so it may be the case that a smaller, cheaper panel could be nearly as effective as well.