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Does anyone know how the medical test at the heart of this legal issue compares to something like the raw data from 23andme? 23andme v4 gives you 25 SNPs for BR
by matt_heimer 11y ago
Does anyone know how the medical test at the heart of this legal issue compares to something like the raw data from 23andme? 23andme v4 gives you 25 SNPs for BRCA1 and BRCA2.
- ihodes 11y agoA comprehensive test looking at the BRCAs may deeply sequence sequence the entire gene(s); spanning around 150 thousand base pairs. You'd not only want to look for SNPs, but novel SNVs, and various structural variants (SVs) and copy-number variants (CNVs). I don't know the most common class of mutations for BRCA1 and 2, so it may be the case that a smaller, cheaper panel could be nearly as effective as well.