I have no doubt your episode was induced by the drug. I also see clear indications that the lack of a safe setting and "sitter" means you set yourself up for a

I have no doubt your episode was induced by the drug. I also see clear indications that the lack of a safe setting and "sitter" means you set yourself up for a much higher risk of a bad experience. Sorry it was so uncomfortable for you. As for cannabis, the condition you're referencing is exceedingly rare. In most cases the ER attendants I've known treating individuals with these symptoms have traced them back to synthetic "legal high" cannabinoid analogues, most of which are untested with an unknown toxicological profile. Their proliferation is a symptom of criminalization, and it is a burgeoning epidemic. I can assure you your 'stomach flu' was not caused by cannabis, however there is some data to back up the link between dysphoria at high dosages and ghrelin (the precursor hormone that makes you hungry) deregulation with consistent usage. My extensive research has turned up no link between cannabis use and an altered micro-biome, but I think it's fair to say both acute and chronic usage can lead to altered/dysfunctional eating patterns. It is also well-known for causing dry mouth, which makes oral hygiene especially important if one wishes to avoid candida-related side effects (occasionally linked with GI upset). Also worth noting, cannabis use in adolescence is correlated with a higher prevalence of anxiety disorders, and can trigger or accelerate latent conditions in those already predisposed to mental illness. It's not all fun and games, but it has a comparatively favorable side-effect profile to most similarly-indicated pharmaceuticals.