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Visualizing the Similarity of Human and Chimp DNA
- PepeGomez 11y agoSorry for a bit off topic coment, but it made me realize that Gattaca consists only of DNA "letters".
- PepeGomez 11y agoOn a second thought, it seems it could be used for 3D shapes in genetic algorithms, with each English letter representing one neighboring voxel. If it hods true that similar DNA results in a similar shape, it could work very well.
- mjburgess 11y agoIt doesnt seem like a lot of thought has gone into making the colour / drawing choice actually visually significant. Eg. given blue is much harder to see here than red, are we over-estimating similarity because there is a lot of red? I suspect they need to talk to some visualization & human vision people to make this compelling.
- pvinis 11y agoLike Pepe said below, each letter spawns in a specific diredtion, so A, or red, always goes up, and you can check that in the beginning, where there are only few lines. so the final shape is more important than color. the color is basically irrelevant, except for the fact that maybe you can see which of A, C, G, T appears more times in that dna sequence.
- learning_still 11y agoCan someone clarify this for me? From watching their video, it seems like all they've done is build a tool that visualizes DNA? I don't understand how the tool assists with visual differences in DNA. I expected maybe a single DNA sequence in one color with the differences highlighted in a contrasting color. Maybe the video just didn't do a good job of explaining things.
- grondilu 11y agoNeat idea. Someone needs to implement that in HTLM5/Webgl. Couldn't resist trying something similar with 2D canvas: https://output.jsbin.com/zorepe https://output.jsbin.com/zorepe It will definitely look better in genuine 3D, but that's a bit more painful. Totally doable, though.
- grondilu 11y agoGave it a shot in HTLM5/WebGL. Check it out: http://grondilu.github.io/dna.html http://grondilu.github.io/dna.html
- aaronmck 11y agoSeems like there are much more intuitive ways to show these differences, something like the plot on Dr. Moran's blog: http://sandwalk.blogspot.com/2012/01/whats-difference-between-human-and.html http://sandwalk.blogspot.com/2012/01/whats-difference-betwee... Although the 3D plots are neat, they kind of feel like 3D barcharts: they add very little over a more straightforward representation (like a heatmap instead).
- AlbertoGP 11y agoThe page was last modified on 27th June 2011, as displayed by Firefox page info dialog. There might be more recent approaches like the one mentioned by aaronmck which is from 2012.