Point of interest, if you do the fundamental physics on neuronal membranes, the number of levels that are actually distinguishable give the noise in the system

Point of interest, if you do the fundamental physics on neuronal membranes, the number of levels that are actually distinguishable give the noise in the system is only about 1000. So even in a biological system there are only 4x the the number of discrete levels. I realize this isn't a good match to what is mentioned in the article but it does put some constraints on the maximum dynamic range that biological sensors have to work within.