There are no completely accurate tumor models. The best a tumor model can do for a group is provide a standardized disease progression to test against. This is

There are no completely accurate tumor models. The best a tumor model can do for a group is provide a standardized disease progression to test against. This is why in mouse tumor models there are a lot of highly aggressive tumor models that are meant to rapidly kill the host-- if you can show even a 5% reduction in tumor size or 5% longer life of the mouse, it's impressive.